RA CAPITAL MANAGEMENT, L.P.
CIK 0001346824
Annualised vol
10.87655%
Beta
0.094324
HHI
783.458517
Top-10 weight
60.41723%
VaR 95%
0.929923%
VaR 99%
2.282428%
Max drawdown
26.634481%
Matched value
93.544516%
Holdings (latest quarter)
| Ticker | Issuer | Class | CUSIP | Value ($) | Weight % | Shares |
|---|---|---|---|---|---|---|
| ASND | ASCENDIS PHARMA A/S | Common Stock | K08588103 | 2,742,280,613 | 23.83 | 1.0281496E7 |
| PBLS | PARABILIS MEDICINES INC | Common Stock | 698955101 | 791,906,364 | 6.88 | 2.8933371E7 |
| RYTM | RHYTHM PHARMACEUTICALS INC | Common Stock | 76243J105 | 740,218,912 | 6.43 | 6666837.0 |
| PCVX | VAXCYTE INC | Common Stock | 92243G108 | 667,018,440 | 5.8 | 1.1474599E7 |
| SION | SIONNA THERAPEUTICS INC | Common Stock | 829401108 | 435,722,930 | 3.79 | 9905045.0 |
| TYRA | TYRA BIOSCIENCES INC | Common Stock | 90240B106 | 389,624,083 | 3.39 | 1.2198625E7 |
| EWTX | EDGEWISE THERAPEUTICS INC | Common Stock | 28036F105 | 340,996,620 | 2.96 | 8392730.0 |
| - | NEWAMSTERDAM PHARMA CO NV | Common Stock | N62509109 | 323,655,973 | 2.81 | 9550191.0 |
| COAG | HEMAB THERAPEUTICS HOLDINGS | Common Stock | 423494103 | 286,810,870 | 2.49 | 7808627.0 |
| SEPN | SEPTERNA INC | Common Stock | 81734D104 | 234,291,284 | 2.04 | 6995858.0 |
| BCAX | BICARA THERAPEUTICS INC | Common Stock | 055477103 | 215,430,432 | 1.87 | 7255993.0 |
| MLYS | MINERALYS THERAPEUTICS INC | Common Stock | 603170101 | 207,550,395 | 1.8 | 7692750.0 |
| GHRS | GH RESEARCH PLC | Common Stock | G3855L106 | 205,277,533 | 1.78 | 7636813.0 |
| IRON | DISC MEDICINE INC | Common Stock | 254604101 | 179,209,164 | 1.56 | 2450221.0 |
| SGP | SPYGLASS PHARMA INC | Common Stock | 85220G109 | 178,550,064 | 1.55 | 8021117.0 |
| ARTV | ARTIVA BIOTHERAPEUTICS INC | Common Stock | 04317A107 | 174,169,727 | 1.51 | 1.7955642E7 |
| JANX | JANUX THERAPEUTICS INC | Common Stock | 47103J105 | 171,873,684 | 1.49 | 1.1189693E7 |
| TSHA | TAYSHA GENE THERAPIES INC | Common Stock | 877619106 | 160,413,963 | 1.39 | 2.3555648E7 |
| BCRX | BIOCRYST PHARMACEUTICALS INC | Common Stock | 09058V103 | 158,271,860 | 1.38 | 1.5827186E7 |
| WVE | WAVE LIFE SCIENCES LTD | Common Stock | Y95308105 | 156,727,684 | 1.36 | 2.6975505E7 |
| - | NUVALENT INC-A | Common Stock | 670703107 | 153,937,316 | 1.34 | 1246456.0 |
| - | ABIVAX SA-ADR | ADR | 00370M103 | 150,924,546 | 1.31 | 1132557.0 |
| ORKA | ORUKA THERAPEUTICS INC | Common Stock | 687604108 | 147,950,996 | 1.29 | 1554597.0 |
| SLDB | SOLID BIOSCIENCES INC | Common Stock | 83422E204 | 120,240,899 | 1.04 | 1.2036126E7 |
| CLYM | CLIMB BIO INC | Common Stock | 28658R106 | 115,026,714 | 1.0 | 8821067.0 |
| ZLAB | ZAI LAB LTD-ADR | ADR | 98887Q104 | 109,127,127 | 0.95 | 5743533.0 |
| SPRY | ARS PHARMACEUTICALS INC | Common Stock | 82835W108 | 86,996,426 | 0.76 | 1.0860977E7 |
| XNCR | XENCOR INC | Common Stock | 98401F105 | 84,915,811 | 0.74 | 5274274.0 |
| JBIO | JADE BIOSCIENCES INC | Common Stock | 008064206 | 81,571,464 | 0.71 | 3671083.0 |
| NTLA | INTELLIA THERAPEUTICS INC | Common Stock | 45826J105 | 76,595,588 | 0.67 | 4526926.0 |
| LBRX | LB PHARMACEUTICALS INC | Common Stock | 50180M108 | 71,680,243 | 0.62 | 2208604.0 |
| DFTX | DEFINIUM THERAPEUTICS INC | Common Stock | 24477V105 | 70,560,000 | 0.61 | 1500000.0 |
| ACRS | ACLARIS THERAPEUTICS INC | Common Stock | 00461U105 | 67,304,808 | 0.58 | 1.2723026E7 |
| - | 4D MOLECULAR THERAPEUTICS IN | Common Stock | 35104E100 | 67,162,061 | 0.58 | 5049779.0 |
| SANA | SANA BIOTECHNOLOGY INC | Common Stock | 799566104 | 65,437,500 | 0.57 | 1.875E7 |
| DMRA | DAMORA THERAPEUTICS INC | Common Stock | 36322Q206 | 62,416,249 | 0.54 | 2399702.0 |
| MNPR | MONOPAR THERAPEUTICS INC | Common Stock | 61023L207 | 61,776,696 | 0.54 | 667207.0 |
| ABOS | ACUMEN PHARMACEUTICALS INC | Common Stock | 00509G209 | 56,050,426 | 0.49 | 2.0992669E7 |
| GERN | GERON CORP | Common Stock | 374163103 | 54,796,481 | 0.48 | 4.2809751E7 |
| RZLT | REZOLUTE INC | Common Stock | 76200L309 | 49,114,203 | 0.43 | 9445039.0 |
| EVMN | EVOMMUNE INC | Common Stock | 30054Y107 | 46,443,739 | 0.4 | 3494638.0 |
| VOR | VOR BIOPHARMA INC | Common Stock | 929033207 | 44,222,569 | 0.38 | 2402095.0 |
| IPSC | CENTURY THERAPEUTICS INC | Common Stock | 15673T100 | 43,498,354 | 0.38 | 1.775443E7 |
| AKTS | AKTIS ONCOLOGY INC | Common Stock | 01021M104 | 42,363,273 | 0.37 | 1314405.0 |
| BIOA | BIOAGE LABS INC | Common Stock | 09077V100 | 40,972,092 | 0.36 | 1671648.0 |
| CCCC | C4 THERAPEUTICS INC | Common Stock | 12529R107 | 37,360,000 | 0.32 | 8000000.0 |
| MIRM | MIRUM PHARMACEUTICALS INC | Common Stock | 604749101 | 37,293,117 | 0.32 | 318554.0 |
| CAPR | CAPRICOR THERAPEUTICS INC | Common Stock | 14070B309 | 36,308,884 | 0.32 | 1507844.0 |
| PEPG | PEPGEN INC | Common Stock | 713317105 | 36,116,181 | 0.31 | 2.0064545E7 |
| PRLD | PRELUDE THERAPEUTICS INC | Common Stock | 74065P101 | 34,516,451 | 0.3 | 6475882.0 |
| CLYM | CLIMB BIO INC | Common Stock | 28658R106 | 32,337,531 | 0.28 | 2479872.0 |
| NKTX | NKARTA INC | Common Stock | 65487U108 | 30,578,515 | 0.27 | 1.0805129E7 |
| QTTB | Q32 BIO INC | Common Stock | 746964105 | 29,715,502 | 0.26 | 2332457.0 |
| AVR | ANTERIS TECHNOLOGIES GLOBAL | Common Stock | 03675P102 | 29,550,000 | 0.26 | 3000000.0 |
| EDIT | EDITAS MEDICINE INC | Common Stock | 28106W103 | 28,800,360 | 0.25 | 8889000.0 |
| OVID | OVID THERAPEUTICS INC | Common Stock | 690469101 | 28,247,604 | 0.25 | 1.0500968E7 |
| ASMB | ASSEMBLY BIOSCIENCES INC | Common Stock | 045396207 | 28,040,867 | 0.24 | 1020410.0 |
| ALXO | ALX ONCOLOGY HOLDINGS INC | Common Stock | 00166B105 | 26,934,527 | 0.23 | 1.3011849E7 |
| BNTC | BENITEC BIOPHARMA INC | Common Stock | 08205P209 | 24,753,000 | 0.22 | 1850000.0 |
| LENZ | LENZ THERAPEUTICS INC | Common Stock | 52635N103 | 23,735,715 | 0.21 | 4178823.0 |
| LXEO | LEXEO THERAPEUTICS INC | Common Stock | 52886X107 | 23,275,000 | 0.2 | 5000000.0 |
| ACRV | ACRIVON THERAPEUTICS INC | Common Stock | 004890109 | 21,768,325 | 0.19 | 1.2229396E7 |
| ALT | ALTIMMUNE INC | Common Stock | 02155H200 | 19,760,000 | 0.17 | 6500000.0 |
| KPTI | KARYOPHARM THERAPEUTICS INC | Common Stock | 48576U205 | 18,732,549 | 0.16 | 1917354.0 |
| DRUG | BRIGHT MINDS BIOSCIENCES INC | Common Stock | 10919W405 | 18,603,000 | 0.16 | 265000.0 |
| AVTX | AVALO THERAPEUTICS INC | Common Stock | 05338F306 | 18,480,000 | 0.16 | 1000000.0 |
| OKUR | ONKURE THERAPEUTICS INC-A | Common Stock | 68277Q105 | 18,232,398 | 0.16 | 3998333.0 |
| FTH | FAETH THERAPEUTICS INC | Common Stock | 81728A207 | 18,050,500 | 0.16 | 722020.0 |
| AURA | AURA BIOSCIENCES INC | Common Stock | 05153U107 | 17,750,000 | 0.15 | 2500000.0 |
| SABS | SAB BIOTHERAPEUTICS INC | Common Stock | 78397T202 | 17,165,850 | 0.15 | 4401500.0 |
| SPTX | SEAPORT THERAPEUTICS INC | Common Stock | 81221K108 | 15,204,000 | 0.13 | 700000.0 |
| PALI | PALISADE BIO INC | Common Stock | 696389402 | 14,889,402 | 0.13 | 7124116.0 |
| - | HELIX ACQUISITION CORP-CL A | Common Stock | G4444S107 | 13,300,000 | 0.12 | 1250000.0 |
| WAY | WAYSTAR HOLDING CORP | Common Stock | 946784105 | 10,868,582 | 0.09 | 529400.0 |
| EQ | EQUILLIUM INC | Common Stock | 29446K106 | 9,908,275 | 0.09 | 3096336.0 |
| MGNX | MACROGENICS INC | Common Stock | 556099109 | 8,612,493 | 0.07 | 1864176.0 |
| - | PERCEPTIVE CAPITAL SOLUTIONS | Common Stock | G70077105 | 8,160,000 | 0.07 | 750000.0 |
| ACET | ADICET BIO INC | Common Stock | 007002207 | 8,057,871 | 0.07 | 932624.0 |
| - | NEWAMSTERDAM PHARMA CO NV-27 | WTS | N62509117 | 7,123,326 | 0.06 | 333333.0 |
| CRVS | CORVUS PHARMACEUTICALS INC | Common Stock | 221015100 | 6,723,000 | 0.06 | 450000.0 |
| RANI | RANI THERAPEUTICS HOLDINGS-A | Common Stock | 753018100 | 6,463,400 | 0.06 | 8500000.0 |
| JATT | JATT II ACQUISITION CORP | Common Stock | G50765109 | 5,680,000 | 0.05 | 500000.0 |
| AMAN | AMANAT ACQUISITION CORP CL A | Common Stock | G0375M101 | 3,810,000 | 0.03 | 375000.0 |
| HOWL | WEREWOLF THERAPEUTICS INC | Common Stock | 95075A107 | 859,349 | 0.01 | 2387744.0 |
| PTN | PALATIN TECHNOLOGIES INC | Common Stock | 696077601 | 670,318 | 0.01 | 62124.0 |
Quarterly portfolios
| Period | Filed | Value ($) | Positions | Vol % | Beta | Max DD % |
|---|---|---|---|---|---|---|
| 2026-06-30 | 2026-08-14 | 11,507,522,068 | 85 | 10.87655 | 0.094324 | 26.634481 |
| 2026-03-31 | 2026-05-15 | 9,437,744,027 | 86 | 11.259391 | 0.104529 | 26.803786 |
| 2025-12-31 | 2026-02-17 | 9,760,868,193 | 72 | 10.154463 | 0.087501 | 23.266195 |
| 2025-09-30 | 2025-11-14 | 8,115,527,458 | 68 | 10.056876 | 0.08389 | 19.485566 |
| 2025-03-31 | 2025-05-15 | 5,987,912,728 | 86 | 10.559126 | 0.090538 | 23.155756 |
| 2024-12-31 | 2025-02-14 | 7,514,204,405 | 90 | 10.380553 | 0.100825 | 27.738716 |