| Nelson Kenza Bemis |
Officer |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
42 |
$40.50 |
6,775 |
| Nilan Nicholas William |
Officer |
10/2/2026 |
Sell |
Direct |
494 |
$24.47 |
466 |
| Nilan Nicholas William |
Officer |
10/2/2026 |
Option Execute |
Direct |
960 |
|
1,426 |
| Nilan Nicholas William |
Officer |
10/2/2026 |
Option Execute |
Direct |
960 |
|
6,711 |
| NIPPON LIFE INSURANCE CO |
|
10/2/2026 |
Buy |
Direct |
187,155 |
$34.27 |
126,604,050 |
| Norman Jessica K |
Officer |
10/2/2026 |
Disposition (Non Open Market) |
Direct |
2,889 |
$34.45 |
34,902 |
| Novikov Sergey |
Officer |
10/2/2026 |
Sell |
Direct |
2,965 |
$5.95 |
48,681 |
| O'BRIEN DEIRDRE |
|
10/2/2026 |
Sell |
Direct |
46,389 |
$333.42 |
136,810 |
| O'Connell Shawn M. |
Director |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
99 |
|
101,311 |
| O'Reilly Timothy M |
|
10/2/2026 |
Sell |
Indirect |
6,282 |
$8.87 |
0 |
| O'Shea Robert J |
|
10/2/2026 |
Buy |
Direct |
65,000 |
$0.96 |
30,483,463 |
| Oakes Patrick Timothy |
Officer |
10/2/2026 |
Disposition (Non Open Market) |
Direct |
882 |
$31.26 |
37,806 |
| Opaleye Management Inc. |
10% Owner |
10/2/2026 |
Buy |
Indirect |
20,000 |
$2.07 |
2,856,963 |
| Orlando Matthew |
Officer |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
35,754 |
$17.20 |
35,754 |
| Orlando Matthew |
Officer |
10/2/2026 |
Disposition (Non Open Market) |
Direct |
14,749 |
$17.20 |
21,005 |
| Ortigas-Wedekind Marga |
Director |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
175,000 |
|
93,750 |
| Osborn Michael Jordan |
Officer |
10/2/2026 |
Buy |
Direct |
10,000 |
$1.91 |
30,000 |
| Owen Taryn R |
Director |
10/2/2026 |
Disposition (Non Open Market) |
Direct |
2,472 |
$9.18 |
789,335 |
| Owens James |
Director |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
268 |
$88.65 |
23,261 |
| Palin Carrie |
|
10/2/2026 |
Sell |
Direct |
5,000 |
$216.43 |
6,660 |
| Pantelick Steven |
|
10/2/2026 |
Sell |
Direct |
23,491 |
$18.97 |
32,526 |
| Parang Touraj |
Director |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
241,252 |
|
1,501,503 |
| Pauls Matthew |
Director |
10/2/2026 |
Sell |
Direct |
786 |
$21.00 |
13,578 |
| Pellegrino Frank G |
|
10/2/2026 |
Buy |
Direct |
245 |
$25.51 |
52,070 |
| PERDUE PETER |
Officer |
10/2/2026 |
Acquisition (Non Open Market) |
Direct |
590 |
|
29,852 |