| O'Day Daniel Patrick |
Director |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
74,461 |
$143.28 |
613,912 |
| O'Neil Christian G. |
|
2/3/2026 |
Option Execute |
Direct |
10,188 |
|
26,585 |
| O'Neil Christian G. |
|
2/3/2026 |
Disposition (Non Open Market) |
Direct |
4,011 |
$120.68 |
22,574 |
| O'Neil Christian G. |
|
2/3/2026 |
Option Execute |
Direct |
10,188 |
|
2,728 |
| O'Neill Lisa M |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
2,600 |
|
36,966 |
| O'Neill Nathan |
Officer |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
166 |
$118.13 |
7,703 |
| O'Reilly David R. |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
84,400 |
|
211,929 |
| O'Reilly David R. |
Officer |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
11,573 |
$79.77 |
144,471 |
| O'Sullivan Colleen M |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
543 |
|
6,950 |
| Oberwager Bradford Scovill |
Director |
2/3/2026 |
Option Execute |
Direct |
1,932 |
$7.86 |
47,021 |
| Oberwager Bradford Scovill |
Director |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
1,601 |
$9.49 |
45,420 |
| Oberwager Bradford Scovill |
Director |
2/3/2026 |
Option Execute |
Direct |
1,932 |
|
0 |
| OCAMPO SUSAN |
|
2/3/2026 |
Sell |
Indirect |
100,000 |
$230.29 |
4,378,323 |
| Ogilby Gary A |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
1,060 |
$674.32 |
3,631 |
| Ohlgart Christiane |
|
2/3/2026 |
Automatic Sell |
Direct |
507 |
$80.73 |
8,247 |
| Okupe Oluyemi |
Officer |
2/3/2026 |
Option Execute |
Direct |
5,262 |
$5.01 |
96,879 |
| Okupe Oluyemi |
Officer |
2/3/2026 |
Automatic Sell |
Direct |
5,262 |
$26.44 |
91,617 |
| Okupe Oluyemi |
Officer |
2/3/2026 |
Option Execute |
Direct |
5,262 |
|
144,051 |
| Olea Carlos A. |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
27,390 |
|
67,996 |
| Olea Carlos A. |
Officer |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
3,869 |
$79.77 |
47,759 |
| Oliver Robin Leigh |
Director |
2/3/2026 |
Disposition (Non Open Market) |
Direct |
134 |
$6.65 |
11,453 |
| OLIVO MARIA |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
10,773 |
|
10,773 |
| OrbiMed Capital GP VIII LLC |
Director |
2/3/2026 |
Automatic Sell |
Indirect |
29,063 |
$44.58 |
3,530,702 |
| Orenstein Gregory |
Officer |
2/3/2026 |
Sell |
Direct |
10,562 |
$18.68 |
451,184 |
| Orf David L |
Officer |
2/3/2026 |
Acquisition (Non Open Market) |
Direct |
2,643 |
|
24,962 |